Management

Prof Dr med Uwe Groß

Phone: 0551 - 39 65801
Fax: 0551 - 39 65861
Email: uwe.gross@med.uni-goettingen.de

General information about the Toxopolasmosis consiliary laboratory

• The Toxoplasma consiliary laboratory is also located at the Institute. The consiliary laboratory is available for the following tasks:
• Consulting services for public health services, laboratories, physicians, patients and research institutes
• Work within the framework of quality assurance (participation in studies and interlaboratory tests)
• Further training offers
• Performance of specific laboratory services (serology and direct pathogen detection)
• Further or new development of diagnostic procedures
• Participation in the epidemiological assessment of the situation by the Robert Koch Institute
• Conducting studies within a network of diagnostic facilities
• Advising the Robert Koch Institute and contributing to the development of scientific materials (e.g. case definitions, RKI guidebook)
• Participation in the working group on toxoplasmosis of the Paul Ehrlich Society

Selected Publikationies:

DaoV.T-V., A. Anagostou, R. Schlösser, U. Rachwalsky, U. Gross, S. Hoehl, V. A. J. Kempf, and Silke Besier. 2023. First description of congenital toxoplasmosis after maternal coinfection with Toxoplasma gondii and severe acute respiratory syndrome coronavirus 2: a case report. J Med Case Rep 17: 121. doi:10.1186/s13256-023-03855-8.

 

Schneider, M.O., F. Faschingbauer, K.O. Kagan, U.Groß, M. Enders, S. Kehl. 2023. toxoplasmois in pregnancy - Recommendations of the AGG (Maternal Diseases Section).Geburtsh. Gynec. 83:1-15.

 

Groß, U., U. Pleyer, D.Schlüter, F. Seeber. 2022. important human parasitoses: toxoplasmosis. Dtsch.Med. Wochenschr. 147: 1012 - 1014.

Garg, M., D. Stern, U. Groß, P.H. Seeberger, F. Seeber, D. Varon Silva. 2019. detection of anti-Toxoplasma gondii antibodies in human sera using synthetic glycosylphosphatidylinositol glycans on a bead-based multiplex assay. Anal Chem. 2019 Aug 12. doi:10.1021/acs.analchem.9b02154.

Mirambo, M.M., S.E. Mshana, U. Gross. 2019. Rubella virus, Toxoplasma gondii and Treponema pallidum congenital infections among full term delivered women in an urban area of Tanzania: a call for improved antenatal care. Afr. Health Sci 19: 1858-1865.

Pleyer, U., U. Groß, D. Schlüter, H. Wilking, F. Seeber. 2019. toxoplasmosis in Germany: epidemiology, diagnosis, risk factors, and treatment. Dtsch Arztebl Int 2019; 116(25): 435-44; DOI:
10.3238/arztebl.2019.0435

Acar İE, Saçar Demirci MD, Gross U*, Allmer J*. 2018. The expressed microRNA-mRNA interactions of Toxoplasma gondii. Front Microbiol. 2018 Jan 4;8:2630. doi: 10.3389/fmicb.2017.02630

RKI Toxoplasmosis Guide (2018), https://www.rki.de/DE/Content/Infekt/EpidBull/Merkblaetter/Ratgeber_Toxoplasmose.html

Gross U, M Enders, JG Garweg, I Reiter-Owona, L Schrod. 2017. toxoplasmosis in pregnancy and the newborn. Gyn. Praxis 42: 43-54.

Völker F, Cooper P, Bader O, Uy A, Zimmermann O, Lugert R, Groß U. 2017. Prevalence of pregnancy-relevant infections in a rural setting of Ghana. BMC Pregnancy Childbirth. 2017 Jun 6;17(1):172. doi: 10.1186/s12884-017-1351-3.

Götze, S., N. Azzouz, Y.H. Tsai, U. Groß, A. Reinhardt, C. Anish, P. H. Seeberger, D. Varón Silva. 2014. diagnosis of toxoplasmosis using a synthetic glycosylphosphatidylinositol glycan. Angew Chem Int Ed Engl. 53: 13701-13705.

Herrmann, D.C., P. Maksimov, A. Hotop, U. Groß,W. Däubener, O. Liesenfeld, U. Pleyer, F. J. Conraths, G. Schares. 2014. genotyping of samples from German patients with ocular, cerebral and systemic toxoplasmosis reveals a predominance of Toxoplasma gondii type II. Int. J. Med. Microbiol. 304: 911-916.

Maenz, M., D. Schlüter, O. Liesenfeld, G. Schares, U. Groß, and U. Pleyer. 2014. ocular toxoplasmosis past, present and new aspects of an old disease. Prog. Retin. Eye Res. 39: 77-106.

Schlüter, D., W. Däubener, G. Schares, U. Groß, U. Pleyer, and C. Lüder. 2014. animals are key to human toxoplasmosis. Int. J.Med. Microbiol. 304: 917-929.

Groß, U. 2013. Pregnancy-related infections. In: Groß, U., and K. Wydra (Eds.) 2013. Maternal-child-health - Interdisciplinary aspects within the perspective of Global Health. Universitätsverlag Göttingen, Göttingen, pp. 191-205.

Janitschke, K., P. Kimmig, H.M. Seitz, M. Frosch, U. Groß, H. Hlobil, I. Reiter-Owona, C. Bogdan, E. Tannich, B. Fleischer, A. Hörauf, R. Ignatius, D. Tappe, J. Walochnik. 2013.
Parasitoses. In Podbielski, A., M. Abele-Horn, M. Herrmann, E. Kniehl, H. Mauch, and H. Rüssmann. Microbiological-infectiological quality standards (MiQ) - Urban und Fischer Verlag, Munich.

Mwambe, B., S. E. Mshana, B. R. Kidenya, A. N. Massinde, H. D. Mazigo, D. Michael, C., and U. Gross. 2013. Sero-prevalence and factors associated with Toxoplasma
gondii infection among pregnant women attending antenatal care in Mwanza, Tanzania. Parasite Vectors. 2013 Aug 6;6:222. doi: 10.1186/1756-3305-6-222

Mylonas, I., U. Groß, H. Hlobil, K. Friese, and U. Wintergerst. 2013. toxoplasmosis. In: Friese, K., I. Mylonas, and A. Schulze (Eds.). Infectious diseases of the pregnant woman and the
newborn. Springer-Verlag, Berlin. S. 481-499. Hotop, A., H. Hlobil, and U. Groß. 2012. efficacy of rapid treatment initiation following primary Toxoplasma gondii infection during pregnancy. Clin. Infect. Dis. 54: 1545-1552.

Maksimov, P., J. Zerweck, A. Maksimov, A. Hotop, U. Groß, U. Pleyer, K. Spekker, W. Däubener, S. Werdermann, O. Niederstrasser, E. Petri, M. Mertens, R. Ulrich, F. Conraths, and G. Schares. 2012. peptide-microarray analysis of in-silico predicted epitopes for the serological diagnosis of Toxoplasma gondii in infected humans. Clin. Vaccine Immunol., 19:865-874.

Maksimov, P., J. Zerweck, A. Maksimov, A. Hotop, U.Groß, K. Spekker, W. Däubener, S. Werdermann, O. Niederstrasser, E. Petri, M. Mertens, R.G. Ulrich, F.J. Conraths, and G. Schares G. 2012. Analysis of clonal type-specific antibody reactions in Toxoplasma gondii seropositive humans from Germany by peptide-microarray. PLoS One 7:e34212. Epub 2012 Mar 28.

Robert, A., K. Hedman, V. Luyasu, J. Zufferey, M.-H.Bessières, R.-M. Blatz, E. Candolfi, A. Decoster, G. Enders, U. Groß, E. Guy,M. Hayde, D. Ho-Yen, J. Johnson, B. Lécollier, A. Naessens, H. Pelloux, P.Thulliez, and E. Petersen. 2001. primary infection with Toxoplasma gondii: a multicentre evaluation of serodiagnostic strategies. Eur. J. Clin. Microbiol. infect. Dis.20: 467-474.

Groß, U., C. G. K. Lüder, V. Hendgen, C. Heeg, I. Sauer, A. Weidner, D. Krczal, and G. Enders. 2000. comparative IgG-antibody profile between mother and child (CGMC test) for diagnosis of congenital toxoplasmosis. J. Clin. Microbiol. 38: 3619-3622.

Reiter-Owona, I., E. Petersen, D. Joynson, H. Aspöck, M.L. Dardé, R. Disko, O. Dreazen, H. Dumon, R. Grillo, U. Groß, M. Hayde, R.Holliman, D. O. Ho-Yen, K. Janitschke, P. Jenum, K. Naser, M. Olszewski, P. Thulliez, and H. M. Seitz. 1999. the past and present role of the Sabin-Feldman dye test in the serodiagnosis.